Tissue adhesive and adhesive tape for pediatric wound closure: A systematic review and meta-analysis
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In brief
In brief
This systematic review and meta-analysis compares tissue adhesive, adhesive tape, and sutures for closing surgical wounds and lacerations in children. All three methods show equivalent infection and dehiscence rates, though adhesive tape may offer marginally better cosmetic outcomes than tissue adhesive.
Written by the GCMD Library team from the article.
Abstract
Background
Tissue adhesive (TiA), adhesive tape (AdT), and sutures can be used to close surgical wounds and lacerations in children. However, it is unclear which technique produces the best results.
Methods
In this prospectively registered study, the PubMed, Ovid MEDLINE, Cochrane Library, Centre for Reviews and Dissemination Database, and ScienceDirect databases were searched. English language studies published between January 1980 and August 2017 evaluating TiA and/or AdT for primary skin closure of surgical wounds or lacerations in patients aged ≤18 years were included. Study endpoints included clinician-rated wound cosmesis and incidence of wound complications.
Results
Thirty-one studies were included in the systematic review and 16 studies in the meta-analysis. Amongst heterogeneous studies, AdT yielded marginally better cosmetic outcomes than TiA (p = 0.04). There was no difference in cosmesis between sutured wounds and those closed with TiA (p = 0.2). No difference in overall risk of wound infection or dehiscence was identified when comparing TiA with AdT (p = 0.3), and TiA with sutures (p = 0.9 and 0.3 respectively).
Conclusions
TiA, AdT, and sutures can all be used for wound closure with equivalent risk of wound infection and dehiscence. AdT appears to convey better cosmesis. Further adequately powered studies directly comparing techniques are required.
Levels of Evidence
Level IV.