The Relationship Between Socioeconomic Status and Omphalocele Prevalence

jpedsurg.org

The omphalocele is a congenital malformation associated with chromosomal abnormalities, however the exact etiology is unknown. Current research has found maternal obesity, diabetes, and African American race as risk factors for omphalocele development and may point to a social determinant of health causative factor. Here we investigate the socioeconomic characteristics of patients with an omphalocele diagnosis and consider epigenetics as the facilitator in its manifestation.

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Article · Jan 2025 · 1 min read

In brief

This study examines the association between socioeconomic status and omphalocele prevalence, exploring how social determinants of health may influence this congenital abdominal wall defect. The research investigates epigenetic mechanisms as potential links between maternal risk factors and omphalocele development in vulnerable populations.

Omphalocele etiology remains unclear despite known association with chromosomal abnormalities.
Maternal obesity, diabetes, and African American race are established risk factors for omphalocele.
Socioeconomic factors may influence omphalocele prevalence through epigenetic mechanisms.
Social determinants of health warrant investigation as potential causative factors in congenital malformations.

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