The Interplay between CD27dull and CD27bright B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory.

In brief

This study characterizes two distinct memory B cell subsets—CD27dull and CD27bright—that change in frequency with age and exhibit different patterns of somatic mutation and antigen specificity. The interplay between these subsets provides the immune system with both flexibility to respond to new antigens and stability to maintain long-term protective immunity.

Written by the GCMD Library team from the article.