The Effect of Absolute Neutrophil Count (ANC) on Early Surgical Site Infection in Implanted Central Venous Catheter (ICVC)
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In brief
In brief
Retrospective study of 1,143 pediatric hematology-oncology patients examining the relationship between preoperative absolute neutrophil count levels and surgical site infection rates following implanted central venous catheter placement. Analysis compared infection outcomes across four patient groups stratified by ANC levels and G-CSF usage at 7 and 30 days post-surgery.
Written by the GCMD Library team from the article.
Purpose
The aim of this study was to evaluate surgical site infection (SSI) rates related to implanted central venous catheters (ICVC) in pediatric hematology and oncology patients with respect to absolute neutrophil count (ANC) levels.
Patients and methods
From January 2004 to December 2015, pediatric patients with ICVC insertion were investigated retrospectively. Patients were divided into four groups according to preoperative ANC levels and Granulocyte-colony stimulating factor (G-CSF) usage. Immediate and early surgical site infections were evaluated 7 and 30 days following surgery.
Results
In total, 1143 patients were enrolled. Patients were placed into 4 groups: 930 patients in group 1 with an ANC≥500/μL without G-CSF, 149 in group 2 with an ANC≥500/μL after G-CSF usage, 36 in group 3 with an ANC