The ABC-D score improves the sensitivity in predicting need for massive transfusion in pediatric trauma patients
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Read the article on jpedsurg.org ↗Article · Nov 2019 · 1 min read
In brief
In brief
This study validates the ABCD scoring system for predicting massive transfusion needs in pediatric trauma patients by adding base deficit and lactate measurements to existing ABC and shock index criteria. The enhanced score achieved 77% sensitivity and 79% specificity, offering improved early identification of children requiring aggressive blood product resuscitation.
Written by the GCMD Library team from the article.
Purpose
Early and accurate identification of pediatric trauma patients who will require massive transfusion (MT) remains difficult, and MT activation criteria are not well established. In children, the addition of shock index-pediatric age-adjusted (SIPA) to the ABC score (ABC-S) only modestly improves the sensitivity of the ABC score. We hypothesized that the discriminate ability of the ABC-S score would improve with the addition of elevated serum lactate and base deficit (ABCD score).
Methods
We identified children between 1 and 18 years old who received a pRBC transfusion between 2008 and 2018 from our trauma registry. We calculated sensitivity, specificity, and accuracy of the ABC, ABC-S, and ABCD scores to determine the need for MT.
Results
We included 211 children, of which 66 required MT. The best predictor of MT was achieved by adding BD and lactate to the ABC-S score, with an AUC of 0.805. An ABCD score of 3 or greater was 77.4% sensitive and 78.8% specific at predicting the need for MT. Pediatric trauma patients that required MT had higher injury severity score (p = 0.005), lactate (p = 0.002), base deficit (p =