Switched memory B cells maintain specific memory independently of serum antibodies: the hepatitis B example.

In brief

This study investigates the persistence of hepatitis B vaccine-induced immunity through memory B cells rather than serum antibody levels. Findings suggest that switched memory B cells maintain protective immunity even when serum antibody titers decline, explaining why breakthrough infections remain rare despite waning antibody levels post-vaccination.

Written by the GCMD Library team from the article.