Surgical resection of infantile hemangiomas following medical treatment with propranolol versus corticosteroids
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In brief
In brief
Retrospective study comparing surgical resection rates for infantile hemangiomas after propranolol versus corticosteroid treatment. Results showed significantly lower surgical intervention rates with propranolol (9%) compared to corticosteroids (27%), supporting propranolol as preferred medical therapy.
Written by the GCMD Library team from the article.
Purpose
There has been a paradigm shift from corticosteroid to propranolol treatment for infantile hemangiomas (IHs), with surgical resection reserved for complicated or persistent IHs. The purpose of this study was to determine if propranolol treatment was associated with decreased utilization of surgical resection compared to corticosteroids.
Methods
A single center retrospective chart review of all corticosteroid or propranolol treated IHs between 2005 and 2014 was performed. Demographic and clinical data were collected. Both univariate and multivariate analyses were performed with the primary outcome of requiring surgical intervention.
Results
Of 652 patients with IH, 52 were treated with oral corticosteroids and 195 with propranolol only. Surgical intervention was required in 14 (27%) of steroid patients vs 18 (9%) of propranolol patients (p