StayCurrentMD · Spontaneous Intestinal Perforations in Extremely Low Birth Weight Infants
Article1 min read·Published Nov 2020Older

Spontaneous Intestinal Perforations in Extremely Low Birth Weight Infants

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Article · Nov 2020 · 1 min read

In brief

In brief

Commentary on increased incidence of spontaneous intestinal perforation in extremely low birth weight infants, questioning institutional factors and management protocols. Author notes SIP cases occurred despite minimal enteral feeding, suggesting factors other than human milk as causative agents.

Written by the GCMD Library team from the article.

I read with interest the article by Fatemizadeh et al [1] describing an increased incidence of spontaneous intestinal perforations (SIP) in their selected cohort. In discussing their findings, I did not find any explanation on why SIP cases were more prevalent in their units? Do they have any management policy or protocol changes during the study period? They did look at the use of vasopressors and indomethacin. However, none of the SIP infants had feeds above trophic feeds which make human milk (HM) less likely to be a cause of SIP.

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