Simple vs. Complex Gastroschisis Outcomes: 30-Year Multicenter Review

jpedsurg.org

Gastroschisis is a congenital abdominal wall defect that has increased in prevalence at birth globally over the past three decades. Despite advancements in neonatal care, gaps remain in understanding the long-term outcomes and factors driving differences between simple (SG) and complex gastroschisis (CG). Previous studies have highlighted disparities in morbidity and mortality between these two groups but lack consistent data over extended periods. This study aims to address these gaps by evaluating outcomes over a 30-year period, hypothesizing that differences in clinical outcomes exist between SG and CG.

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Article · Jun 2025 · 1 min read

In brief

This multicenter study examines 30 years of data comparing simple versus complex gastroschisis cases to identify outcome differences and prognostic factors. The research addresses critical knowledge gaps in long-term morbidity and mortality patterns for this increasingly prevalent congenital abdominal wall defect.

Gastroschisis prevalence has risen globally over 30 years despite improved neonatal care.
Complex gastroschisis (CG) shows worse outcomes than simple gastroschisis (SG) but data gaps persist.
Long-term outcome differences between SG and CG remain poorly understood across extended periods.
30-year multicenter review aims to clarify clinical outcome disparities between simple and complex cases.
Consistent longitudinal data is needed to guide management strategies for gastroschisis subtypes.

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