Should we reduce routine surveillance imaging in pediatric germ cell tumors?
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Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Mar 2023 · 1 min read
In brief
In brief
This retrospective study of the TCGM-AIEOP-2004 cohort demonstrates that serum tumor markers detected over 70% of relapses in pediatric malignant germ cell tumors, rising to over 90% in specific subgroups. The findings support reducing routine surveillance imaging in selected patients, potentially decreasing cumulative radiation exposure during follow-up.
Written by the GCMD Library team from the article.
This paper retrospectively investigated the site and the detection method of relapses in children and adolescents with malignant germ cell tumors enrolled in the TCGM-AIEOP-2004 Study and subsequently developed a relapse, in order to evaluate a possible reduction in radiological exposure during follow-up. Including all malignant cases, serum tumor markers identified a relapse in more than 70% and, according to the selection criteria published by Children Oncology Group in 2018, in more than 90% of cases. These results confirm the importance of serum tumor markers as a relapse detection method, with possible reduction of radiology exams in specific subgroups.
DOI: 10.1002/pbc.30200