Sex differences in children operated with pyeloplasty for pelvoureteric junction obstruction
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In brief
In brief
This retrospective study of 194 pediatric pyeloplasty cases reveals significant sex-based differences in UPJO presentation and outcomes. Girls more frequently present with preoperative infections (17.2% vs 7.0%), while boys present with pain more often (47.4% vs 25.0%) and have higher reoperation rates (all 9 reoperations were boys).
Written by the GCMD Library team from the article.
Abstract
Purpose
Pelvoureteric junction obstruction (UPJO) is a common cause of hydronephrosis in children but no previous studies have evaluated differences between boys and girls operated with pyeloplasty. This study aimed to evaluate potential differences between sexes in children operated with pyeloplasty for PUJO in terms of presentation, surgery, and long-term results.
Methods
Data was retrospectively collected from all children operated on with pyeloplasty between January 2002 and December 2020. Data contained several variables covering presentation, surgery, and long-term results.
Results
In total, 194 patients were included of which 126 (64.9%) were boys. There were no significant differences in prenatal findings, pelvic dilation on ultrasound, function of the affected kidney, surgical method, obstruction type, resolution of hydronephrosis, or improvement of function. Boys presented with pain more often than girls (47.4 vs 25.0%, p < 0.01) while girls were more prone to infections preoperatively (17.2 vs 7.0%, p = 0.04). All nine patients requiring reoperation were boys (p = 0.03).
Conclusion
Girls with UPJO seem to experience infections as presenting symptoms more often than boys, while boys significantly more often present with pain. There is also a higher percentage of boys needing reoperation.