Scoliosis after thoracotomy repair of esophageal atresia: a systematic review
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In brief
In brief
Systematic review of 1338 children shows scoliosis develops in approximately 13% of patients after thoracotomy repair of esophageal atresia/TEF, with curvature typically convex to the left. Most cases are mild and do not require intervention, though 10 patients underwent spinal surgery. Uncertainty remains whether thoracoscopic techniques can prevent this complication.
Written by the GCMD Library team from the article.
Abstract
Standard surgical repair of esophageal atresia/tracheoesophageal fistula (EA/TEF) is via a right posterolateral thoracotomy. A recognized complication is the later development of scoliosis. The prevalence and pathogenesis of secondary scoliosis are poorly understood. We, therefore, conducted a systematic review on this topic. All English language articles reporting incidence, outcomes and/or interventions for scoliosis in children after EA repair via thoracotomy were identified. Fourteen relevant articles published between 1969 and 2019 reporting 1338 children were included in the analysis. The aggregate prevalence of scoliosis among 937 children without congenital vertebral anomalies was 13%, but this figure varied widely between studies. Severity of scoliosis was documented in 181 children; eight children had a Cobb angle > 40° and 10 had undergone spinal surgery. The spinal curvature in affected individuals was dominantly or exclusively convex to the left. In conclusion, the reported prevalence of scoliosis varies widely but on average affects about one in eight children after open repair of EA/TEF. Most cases are mild and do not require intervention. It is currently uncertain whether secondary scoliosis is preventable by using meticulous thoracotomy techniques or thoracoscopic repair.
Level of evidence IV.