StayCurrentMD · Risk factors associated with recent opioid-related hospitalizations in children: a nationwide analysis
Article1 min read·Published Mar 2022Older

Risk factors associated with recent opioid-related hospitalizations in children: a nationwide analysis

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Article · Mar 2022 · 1 min read

In brief

In brief

Nationwide study of 51,349 pediatric opioid-related hospitalizations found that 17% had prior admissions within the same year, with most occurring at the same hospital. Drug abuse, chronic pulmonary disease, and depression were the most common comorbidities, while only 16% had recent surgery—highlighting non-surgical opioid exposure as a major risk factor in children.

Written by the GCMD Library team from the article.

Abstract

Purpose

Identifying at-risk children can provide a crucial opportunity for preventative measures to avoid opioid addiction. This study sought to determine at-risk pediatric patients that were previously hospitalized due to other causes prior to their opioid-related admission.

Methods

The Nationwide Readmissions Database (2010–2014) was queried for children 1–18 years old with an opioid-related hospitalization. Previous admissions (up to 1 year prior) and associated diagnoses were compared. Results were weighted for national estimates.

Results

51,349 opioid-related hospitalizations were identified with an overall in-hospital mortality of 0.8%. Seventeen percent had a previous admission during the same calendar year of which 44% had > 1 and 11% had ≥ 5 prior admissions. Only 4% of prior admissions occurred at a different hospital. Males and females were equally represented, and 82% were ≥ 13 years old. Only 16% of previously admitted patients underwent a major surgical procedure during a previous hospitalization. The most common concomitant diagnoses for patients with prior hospitalizations were drug abuse (37%), chronic pulmonary disease (18%), and depression (10%).

Conclusion

Opioid-related hospitalizations often occur among children with multiple recent admissions, usually to the same hospital. Most patients do not have a history of cancer or recent surgery to account for their opioid use.

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