Quality of life after esophageal replacement in children
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In brief
In brief
Study of 14 patients who underwent esophageal replacement for long gap esophageal atresia found that most achieved normal quality of life scores comparable to healthy controls, regardless of surgical technique (gastric pull-up or jejunum interposition). Postoperative complications like heartburn and dysphagia did not significantly impact long-term quality of life outcomes.
Written by the GCMD Library team from the article.
Abstract
Purpose
Assessing quality of life (QoL) after esophageal replacement (ER) for long gap esophageal atresia (LGEA).
Methods
All patients after ER for LGEA with gastric pull-up (GPU n = 9) or jejunum interposition (JI n = 14) at the University Medical Center Groningen and Utrecht (1985–2007) were included. QoL was assessed with 1) gastrointestinal-related QoL using the Gastrointestinal Quality of Life Index (GIQLI)), 2) general QoL (Child Health questionnaire CHF87-BREF (children)/World Health Organization questionnaire WHOQOL-BREF (adults)), and 3) health-related QoL (HRQoL) (TNO AZL TACQoL/TAAQoL). Association of morbidity (heartburn, dysphagia, dyspnea on exertion, recurrent cough) and (HR)QoL was evaluated.
Results
Six patients after GPU (75%) and eight patients after JI (57%) responded to the questionnaires (mean age 15.7, SD 5.9, 12 male, two female). Mean gastrointestinal, general and health-related QoL total scores of the patients were comparable to healthy controls. However, young adults reported a worse physical functioning (p = 0.02) but better social functioning compared to peers (p = 0.01). Morbidity was not associated with significant differences in (HR)QoL.
Conclusions
With the current validated QoL most patients after ER with GPU and JI for LGEA have normal generic and disease specific QoL scores. Postoperative morbidity does not seem to influence (HR)QoL.
Type of Study
Prognosis Study.
Level of evidence
III.