Prognostic value of the oxygenation index to predict survival and timing of surgery in infants with congenital diaphragmatic hernia
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In brief
In brief
Retrospective study evaluating oxygenation index measurements in the first 48 hours after birth as predictors of 30-day mortality and optimal surgical timing in infants with antenatally diagnosed CDH. Analysis compares mean versus best OI on day 1 and correlates serial OI values with surgical outcomes, ventilation duration, and hospital length of stay.
Written by the GCMD Library team from the article.
Aims
To compare the mean oxygenation index on day1 (MOId1) with the best OI on day1 (BOId1) in predicting 30-day mortality in congenital diaphragmatic hernia (CDH). In addition, to determine whether serial OIs in the first 48 h after birth and preoperative OI (PreOp-OI), were associated with optimal timing of surgery, ventilation requirement and hospital stay in infants with CDH.
Methods
The medical records of infants with antenatally diagnosed CDH during 2009–2015 were retrospectively reviewed. Receiver operator characteristic curves were constructed to identify MOId1 and BOId1 cutoff levels to predict 30-day mortality. In those who underwent surgery, the mean OI on each of the first two days (MOId1, MOId2) and PreOp-OI were correlated using Spearman (rs) with the age at surgery, the duration of ventilation and length of stay. Statistical significance was P