Predictors of early lobectomy after birth in prenatally diagnosed congenital pulmonary airway malformation
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In brief
In brief
Retrospective analysis of 36 prenatally diagnosed CPAM cases examining the relationship between congenital pulmonary airway malformation volume ratio and timing of postnatal lobectomy. Macrotype CCAM with CVR >2.0 strongly predicted need for emergent or urgent neonatal surgery, while bronchial atresia cases typically underwent elective procedures.
Written by the GCMD Library team from the article.
Purpose
The purpose of this study was to clarify the relationship between congenital pulmonary airway malformation volume ratio (CVR) of bronchial atresia (BA), CVR of congenital cystic adenomatoid malformations (CCAM), and time of surgery after birth.
Method
We retrospectively analyzed data of 36 BA and CCAM cases, prenatally diagnosed as CPAM from 2009 through 2014.
Results
Within 2 h after birth, 12 neonatal patients underwent emergent (EMG) lobectomy. Five cases of lobectomy were performed urgently (UG) from 12 to 48 h after birth. Four cases of lobectomy were required within 30 days after birth (early = EAG). We performed lobectomy in 15 other patients at 11 months after birth (late = LG). Of the EMG cases, 11 were macrotype CCAM (maximal CVR >2.0), and 4 of 5 UG cases were microtype CCAM (CVR >2.0). Of the EAG cases, 3 of 4 were macrotype CCAM with CVR of 2.0. By contrast, elective surgery was performed in most BA cases.
Level of evidence
IV.