Predictive value of oxygenation index for outcomes in left-sided congenital diaphragmatic hernia
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Read the article on jpedsurg.org ↗Article · Feb 2018 · 1 min read
In brief
In brief
Retrospective study of 50 left-sided CDH patients evaluates whether highest oxygenation index in first 48 hours of life predicts survival and morbidity better than prenatal imaging markers like lung-to-head ratio and liver herniation percentage. Findings inform early risk stratification for neonatal management.
Written by the GCMD Library team from the article.
Background & objectives
Congenital Diaphragmatic Hernia (CDH) is associated with significant morbidity and mortality. This study compares the efficacy of the highest oxygenation index in the first 48 h (HiOI) versus current prenatal indices to predict survival and morbidity.
Methods
Medical records of 50 prenatally diagnosed, isolated, left-sided CDH patients treated from January 2011 to April 2016 were reviewed. Data abstracted included HiOI, lung to head ratio (LHR), observed to expected total fetal lung volume (O/E TFLV), percent liver herniation (%LH), 6 month survival, respiratory support at discharge, ventilator days and length of stay. Data were analyzed using parametric and nonparametric tests and regression analyses as appropriate.
Results
HiOI was associated with significantly increased LOS (p