Polypoid disease of colon in children
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Read the article on link.springer.com ↗Article · Jan 2020 · 1 min read
In brief
In brief
Review of colonic polypoid disease in pediatric patients, distinguishing benign juvenile polyps from inherited polyposis syndromes with malignant potential. Discusses diagnostic approaches including genetic testing and colonoscopy, and compares surgical management options for familial adenomatous polyposis, including timing and technique selection for prophylactic colectomy.
Written by the GCMD Library team from the article.
Abstract
Polyps in gastrointestinal tract are mostly benign and result from hamartomas or lymphoid hyperplasia of submucosa. They usually occur as isolated lesions in children and are referred to as juvenile polyps. Multiple polyps with inherited origin are called polyposis and can be seen as a part of the syndrome. The polyps with adenomatous histopathology have malignant potential and necessitate genetic testing and colonoscopy to define the risk of cancer. Although simple endoscopic removal is adequate in the treatment of juvenile polyps, children with familial adenomatous polyposis (FAP) need total colectomy with ileorectal anastomosis (IRA) or ileal pouch-anal anastomosis (IPAA). The timing of prophylactic colectomy and the type of surgical treatment are controversial in children. The clinical features, the assessment of cancer risk, and the alternatives of the surgical treatment of polyps are reviewed in this paper.