StayCurrentMD · PIgR Autoantibody-abundant Circulating Vesicles Contributes to Biliary Injury in Biliary Atresia
Article1 min read·Published Dec 2024

PIgR Autoantibody-abundant Circulating Vesicles Contributes to Biliary Injury in Biliary Atresia

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Article · Dec 2024 · 1 min read

In brief

In brief

This research investigates how autoantibodies against polymeric immunoglobulin receptor (pIgR) carried in circulating vesicles contribute to bile duct damage in biliary atresia, a rare pediatric cholestatic condition. The findings may reveal novel autoimmune mechanisms underlying BA pathogenesis and progression.

Written by the GCMD Library team from the article.

This study aimed to elucidate the role of polymeric immunoglobulin receptor (pIgR) autoantibodies in the pathogenic progression of biliary atresia (BA).

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