StayCurrentMD · Perspectives of Boys, Families & Surgeons: Preputioplasty vs. Circumcision for Treatment of Lichen Sclerosus
Article1 min read·Published Sep 2025

Perspectives of Boys, Families & Surgeons: Preputioplasty vs. Circumcision for Treatment of Lichen Sclerosus

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Article · Sep 2025 · 1 min read

In brief

In brief

This study examines patient, family, and surgeon perspectives on two surgical approaches for treating lichen sclerosus (BXO) in boys: preputioplasty with intralesional steroids versus circumcision. The research aims to inform the design of a randomized controlled trial by understanding stakeholder experiences and preferences regarding these treatment options.

  • Patient and family perspectives are essential when comparing preputioplasty with intralesional steroids versus circumcision for lichen sclerosus.
  • Surgeon input is critical for designing feasible RCTs comparing foreskin-preserving versus excisional approaches to pediatric LS/BXO.
  • Shared decision-making requires understanding how boys and families weigh tissue preservation against recurrence risk in LS treatment.
  • Preputioplasty with intralesional steroids offers a foreskin-sparing alternative to circumcision for select lichen sclerosus cases.
  • Qualitative research on treatment preferences informs patient-centered trial design in pediatric urologic conditions like BXO.

Written by the GCMD Library team from the article.

I) to explore experiences of boys and parents/guardians regarding surgical treatment options for lichen sclerosus et atrophicus (LS / BXO); ii) to gather surgeons' perspectives to inform design of a randomized controlled trial (RCT) comparing preputioplasty with intralesional steroids (PIT) versus circumcision to treat LS.

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