Perioperative and long-term functional outcomes of neonatal versus delayed primary endorectal pull-through for children with Hirschsprung disease: A Pediatric Colorectal and Pelvic Learning Consortium Study
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In brief
In brief
Comparative study from the PCPLC registry examining perioperative morbidity and long-term functional outcomes between neonatal versus delayed primary endorectal pull-through for Hirschsprung disease. Analysis evaluates whether delayed surgery offers advantages in preventing enterocolitis and improving bowel function while allowing families time to prepare for the procedure.
Written by the GCMD Library team from the article.
Background/Purpose
: The timing of endorectal pull-through for Hirschsprung disease (HD) is controversial. Neonatal primary endorectal pull-through theoretically prevents preoperative enterocolitis. Delayed primary endorectal pull-through offers the surgeon the benefit of more robust perineal anatomy and allows primary caregivers the time to emotionally process the diagnosis and to gain experience with rectal irrigations. We hypothesized that delayed primary endorectal pull-through would be associated with equivalent perioperative morbidity compared to the neonatal repair and would lead to improved long-term functional outcomes.
Methods
: We analyzed all patients in the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) registry who had a primary endorectal pull-through for HD and at least three-and-one-half years of follow up in a specialty colorectal clinic. We evaluated patient demographics, operative outcomes, perioperative episodes of enterocolitis, and long-term functional outcomes for the neonatal (
