Pediatric Trauma-Related Coagulopathy: Balanced Resuscitation, Goal-Directed Therapy and Viscoelastic Assays
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In brief
In brief
This review examines trauma-induced coagulopathy management in pediatric patients, focusing on damage-control resuscitation strategies adapted from adult evidence. Key topics include age-specific hemostatic differences, balanced resuscitation protocols, viscoelastic assays for real-time coagulation monitoring, and tranexamic acid use for hemorrhage control in injured children.
Written by the GCMD Library team from the article.
Publication date: Available online 23 January 2019
Source: Seminars in Pediatric Surgery
Author(s): Natalie A. Drucker, S. Keisin Wang, Christopher Newton
Abstract
The improved understanding of trauma-induced coagulopathy in adults has led to an evolution in the strategies of damage-control resuscitation. While its impact on the care of pediatric trauma patients is of tremendous interest, the evidence is sparse, and a great deal of research is still needed in this domain. Areas of particular interest include age-related differences in hemostasis and balanced resuscitation, advances in functional coagulation assays and effective adjunctive medications, such as tranexamic acid, for hemorrhage control. This review examines the available pediatric data, reviews applicable adult data, and introduces areas of investigation that will impact pediatric trauma care in the future.