Pediatric trauma-associated acute respiratory distress syndrome: Incidence, risk factors, and outcomes
jpedsurg.org shows its articles on its own site.
Read the article on jpedsurg.org ↗Article · Jul 2018 · 1 min read
In brief
In brief
Analysis of 488,381 pediatric trauma cases reveals PT-ARDS occurs in 0.5% of patients with 18.6% mortality, predominantly within the first week post-injury. Key risk factors include nonaccidental trauma, near drowning, severe head/chest injury, and sepsis, with PT-ARDS independently associated with 33% increased mortality risk after adjustment for confounders.
Written by the GCMD Library team from the article.
Background/Purpose
Acute Respiratory Distress Syndrome (ARDS) results in significant morbidity and mortality in pediatric trauma victims. The objective of this study was to determine risk factors and outcomes specifically related to pediatric trauma-associated ARDS (PT-ARDS).
Methods
A retrospective cohort (2007–2014) of children ≤18 years old from the American College of Surgeons National Trauma Data Bank (NTDB) was used to analyze incidence, risk factors, and outcomes related to PT-ARDS.
Results
PT-ARDS was identified in 0.5% (2660/488,381) of the analysis cohort, with an associated mortality of 18.6% (494/2660). Mortality in patients with PT-ARDS most commonly occurred in the first week after injury. Risk factors associated with the development of PTARDS included nonaccidental trauma, near drowning, severe injury (AIS ≥ 3) to the head or chest, pneumonia, sepsis, thoracotomy, laparotomy, transfusion, and total parenteral nutrition use. After adjustment for age, injury complexity, injury mechanism, and physiologic variables, PT-ARDS was found to be independently associated with higher mortality (adjusted OR 1.33, 95% CI 1.18–1.51, p