OUTCOMES OF PATENT DUCTUS ARTERIOSUS LIGATION IN VERY LOW BIRTH WEIGHT PREMATURE INFANTS: A RETROSPECTIVE COHORT ANALYSIS
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In brief
In brief
Retrospective cohort study evaluating outcomes of surgical PDA ligation in very low birth weight premature infants who failed medical management. Study addresses ongoing controversy around optimal timing and surgical decision-making for hemodynamically significant PDA in this high-risk neonatal population.
Written by the GCMD Library team from the article.
Introduction
Patent ductus arteriosus (PDA) can be a significant hemodynamic problem in preterm infants leading to increased morbidity and mortality. PDA ligation is therefore considered an urgent procedure in infants who have failed medical therapy. However, there is controversy regarding optimal timing and decision to operate. This study aimed to evaluate the outcomes and efficacy of PDA ligation in very low birth weight premature infants.
Methods
We performed a retrospective review of our institution's database and included very low birth weight premature infants (