Oral Antibiotic Exposure and the Risk of Overweight and Obesity in Children with Vesicoureteral Reflux

jpedsurg.org

Continuous antibiotic prophylaxis (CAP) is widely used in children with vesicoureteral reflux (VUR) to prevent recurrent urinary tract infections, but its long-term metabolic effects are uncertain. We evaluated whether oral antibiotic exposure is associated with overweight and obesity in young children with VUR.

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Article · Feb 2026 · 1 min read

In brief

This study examines the potential link between long-term continuous antibiotic prophylaxis (CAP) and weight gain in pediatric patients with vesicoureteral reflux. The research addresses an important gap in understanding the metabolic consequences of prolonged antibiotic exposure used to prevent recurrent UTIs in this population.

Continuous antibiotic prophylaxis (CAP) is commonly prescribed in pediatric VUR to prevent recurrent UTIs.
Long-term metabolic consequences of CAP in children with VUR remain poorly understood.
Study investigates association between oral antibiotic exposure and increased weight in young VUR patients.
Findings may inform risk-benefit discussions when prescribing prolonged antibiotic prophylaxis in pediatric urology.

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