OESOPHAGEAL ATRESIA WITH VERY LOW BIRTH WEIGHT: CLINICAL CHARACTERISTICS AND LONG-TERM OUTCOME
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In brief
In brief
Retrospective study of 327 esophageal atresia patients (1980-2020) found that very low birth weight infants (≤1500g, 10% of cohort) had significantly higher one-month mortality (35% vs 4%) and increased incidence of congenital heart disease and chromosomal abnormalities compared to higher birth weight patients.
Written by the GCMD Library team from the article.
Aim of the Study
An assessment of the clinical data and outcome of patients with oesophageal atresia (OA) with very low birth weight (VLBW) was completed.
Method
With ethical consent, we reviewed the records of 327 successive patients with OA from 1980 to 2020. Main outcome measures survival and oesophageal repair were compared between patients with VLBW(≤1500g) and with BW>1500g.
Results
Thirty-four (10%) patients had VLBW. Gross types of OA in VLBW were similar as in other patients: A (15%/7%), B (3%/3%), C (78%/82%), D (3%/4%), E (0%/7%), F (0%/1%) (p=0.16–0.99). In VLBW the incidence of congenital heart disease (CHD) (47%) and trisomy 13/18 and Cri du Chat (15%) were higher than in BW>1500g (23% and 1%), (p = 0.001 both). In VLBW one-month mortality was 35% vs 4% in patients with BW>1500g (p