Nutritional and pharmacological strategy in children with short bowel syndrome
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In brief
In brief
This review examines short bowel syndrome management in neonates following major intestinal resection. It details the intestinal adaptation process and evidence-based nutritional and pharmacological strategies to optimize digestive function recovery and support enterocyte stimulation through enteral feeding.
Written by the GCMD Library team from the article.
Abstract
Short bowel syndrome in neonates is a severe and life-threatening disease after a major loss of small bowel with or without large bowel. Intestinal adaptation, by which the organism tries to restore digestive and absorptive capacities, is entirely dependent on stimulation of the active enterocytes by enteral nutrition. This review summarizes recent knowledge about the pathophysiologic consequences after the loss of different intestinal parts and outlines the options for enteral nutrition and pharmacological therapies to support the adaptation process.