Newborn and Infant Parasympathetic Evaluation (NIPE™) Monitor for Assessing Pain During Surgery and Interventional Procedures: A Systematic Review

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The heart rate variability-derived Newborn Infant Parasympathetic Evaluation (NIPE) monitor has been designed to be an objective, non-invasive tool for the assessment of pain and discomfort in children under 2 years of age. The aim of this systematic review was to evaluate the ability of NIPE to assess pain in neonates and infants during surgical and/or painful procedures.

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Article · Dec 2023 · 1 min read

In brief

This systematic review evaluates the NIPE monitor, a heart rate variability-based tool designed to objectively assess pain and discomfort in children under 2 years during surgical and interventional procedures. The review examines evidence for NIPE's clinical utility as a non-invasive alternative to subjective pain scales in neonatal and infant populations.

NIPE monitor uses heart rate variability to objectively assess pain in children under 2 years old non-invasively.
Designed specifically for neonatal and infant populations where self-reporting of pain is impossible.
Systematic review evaluates NIPE's clinical utility during surgical procedures and painful interventions.
Provides objective pain assessment alternative to behavioral scales in pre-verbal patients.
Parasympathetic nervous system activity serves as physiologic marker for pain and discomfort in infants.

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