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More Evidence Against Appendectomy at the Time of a Ladd Procedure
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Read the article on jpedsurg.org ↗Article · May 2022 · 1 min read
In brief
In brief
This article challenges the routine practice of prophylactic appendectomy during Ladd procedures for intestinal malrotation. Emerging evidence suggests the appendix plays important immunological roles in gastrointestinal health and GALT function, with recent data linking appendectomy to increased lifetime sepsis risk in children.
Written by the GCMD Library team from the article.
It may be time that our specialty recognizes that the vermiform appendix is not just a rudimentary organ without function. Many studies have suggested its importance for gastrointestinal health and as a unique part of the gut associated lymphoid tissue (GALT) that is likely different from lymphoid tissue in other parts of the intestine. [1] This notion has been further substantiated by a recent article, “Children with appendectomy have increased risk of future sepsis, real world data in Taiwan.” [2] The group in Taiwan applied a nationwide population-based cohort to assess whether children who received appendectomy were at increased risk of subsequent sepsis during their lifetime.
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