Major abdominal wall defects in the low- and middle-income setting: current status and priorities
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In brief
In brief
This review examines the stark mortality disparity for gastroschisis and omphalocele between high-income countries (<5%) and low-middle income countries (30-100%), where these defects represent up to 21% of emergency neonatal cases. The article assesses current best practices and identifies priorities for improving outcomes in resource-limited settings.
Written by the GCMD Library team from the article.
Abstract
Major congenital abdominal wall defects (gastroschisis and omphalocele) may account for up to 21% of emergency neonatal interventions in low- and middle-income countries. In many low- and middle-income countries, the reported mortality of these malformations is 30–100%, while in high-income countries, mortality in infants with major abdominal wall reaches less than 5%. This review highlights the challenges faced in the management of newborns with major congenital abdominal wall defects in the resource-limited setting. Current high-income country best practice is assessed and opportunities for appropriate priority setting and collaborations to improve outcomes are discussed.