Long-term Outcomes of Botulinum Toxin Injection Into the External Anal Sphincters: An Effective New Treatment of Chronic Functional Constipation in Children

In brief

This study evaluates botulinum toxin injection into the external anal sphincter as a treatment for children with chronic functional constipation that has not responded to standard medical management. The research examines both immediate and extended follow-up results of this minimally invasive intervention for refractory cases.

• Botulinum toxin injection into external anal sphincter is an established treatment for refractory chronic functional constipation in children
• BT therapy targets children who have failed standard medical management and continue to experience soiling
• Study evaluates both immediate post-injection outcomes and durability of symptom relief over extended follow-up periods
• EAS injection approach offers minimally invasive alternative to more aggressive surgical interventions for severe pediatric constipation

Written by the GCMD Library team from the article.