Long-term growth outcomes in neonates diagnosed with necrotizing enterocolitis: a 20-year analysis
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Read the article on jpedsurg.org ↗Article · Feb 2019 · 1 min read
In brief
In brief
Retrospective 20-year cohort study of 527 neonates (294 NEC cases, 233 matched controls) examines longitudinal growth outcomes in necrotizing enterocolitis survivors. Study includes Bell stage I-III cases with median gestational age 29 weeks and birth weight 1237g, analyzing length and weight trajectories from birth through two decades of follow-up.
Written by the GCMD Library team from the article.
Purpose
Limited data exists for longitudinal growth outcomes in neonates with a history of necrotizing enterocolitis (NEC). We aimed to study 20-year growth outcomes in NEC survivors.
Methods
A retrospective matched cohort study included neonates diagnosed with NEC and control subjects matched for birth year, birth weight, and gestational age who had at least one post-discharge follow-up. The primary outcome was growth, measured by length and weight until 20 years. Logistic regression was used to test the change in growth from birth until most recent encounter.
Results
Five hundred twenty-seven neonates were included: 294 with NEC, and 233 controls. Sixty-eight percent of NEC cases were Bell's stage I, 25% were stage II, and 7% were stage III. Median gestational age was 29 weeks, and median birth weight was 1237 g. Infants with NEC had a longer NICU stay (p