From
Dr. Michael Helmrath
Localized intestinal radiation and liquid diet enhance survival and permit evaluation of long-term intestinal responses to high dose radiation in mice
pubmed.ncbi.nlm.nih.gov shows its articles on its own site.
Read the article on pubmed.ncbi.nlm.nih.gov ↗Article · Nov 2026 · 1 min read
In brief
In brief
This study describes a novel murine model using localized intestinal radiation combined with liquid diet to enable survival after high-dose radiation exposure. The method allows investigation of intestinal stem cell loss, crypt regeneration, and long-term epithelial repair mechanisms that would otherwise be lethal.
Written by the GCMD Library team from the article.
The segment radiation method provides a useful model to study ISC/crypt loss and long-term crypt regeneration and epithelial repair, and may be valuable for future application to ISC transplantation or to genetic mutants that would not otherwise survive radiation doses that lead to complete crypt lo …
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