StayCurrentMD · Letter to the Editor
Article1 min read·Published Jun 2019Older

Letter to the Editor

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Article · Jun 2019 · 1 min read

In brief

In brief

Letter discussing the association between congenital diaphragmatic hernia (CDH) and undescended testes (UDT), examining potential causal mechanisms including embryological defects near the urogenital ridge and iatrogenic factors from surgical repair leading to acquired cryptorchidism.

Written by the GCMD Library team from the article.

I read with interest the report by Janssen et al [1], showing a strong link between congenital diaphragmatic hernia (CDH) and undescended testes (UDT), both congenital and acquired. The authors cite five possible causal mechanisms between CDH and UDT, including absence of diaphragm tissue close to the urogenital ridge, leading to both CDH and UDT. Another possible cause was possible scar formation after surgical correction of the diaphragm pulling up the retroperineum, leading to ascending, acquired UDT.

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