Laparotomy complications on extracorporeal life support: Surgical site bleeding does not increase mortality
jpedsurg.org shows its articles on its own site.
Read the article on jpedsurg.org ↗Article · May 2019 · 1 min read
In brief
In brief
This ELSO database study of 196 pediatric patients examined laparotomy outcomes during extracorporeal life support, finding that surgical site bleeding did not independently increase mortality risk. Lower gestational age, infectious complications, and nonsurgical hemorrhage were identified as significant mortality predictors in this high-risk population.
Written by the GCMD Library team from the article.
Purpose
The risks of laparotomy during extracorporeal life support (ECLS) are poorly defined. We examined risk factors associated with bleeding and mortality after laparotomy on ECLS.
Methods
The Extracorporeal Life Support Organization (ELSO) database was queried for all pediatric patients [0–17 years] with a procedure code for laparotomy. Outcome data were analyzed to define factors contributing to laparotomy complications and mortality while on ECLS. Univariate and multivariate analyses were applied to determine independent risk factors.
Results
196 patients who met inclusion criteria were identified. The mortality rate in the entire cohort was 67.3%. In both univariate and multivariate analyses, surgical site bleeding did not significantly increase the risk of mortality (OR 0.8; 95% CI 0.4–1.7). Logistic regression analysis revealed that lower gestational age, infectious complications and nonsurgical site hemorrhagic complications were independently increased mortality risk (all p