Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system

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Amr Moursi

Arginine methylation is a post-translational modification that consists of the transfer of one or two methyl (CH3) groups to arginine residues in proteins. Several types of arginine …

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Article · Jul 2026 · 1 min read

In brief

This study examines the effects of arginine methylation inhibitors on fresh brain tumor tissue samples maintained in a miniaturized perfusion culture system. The research investigates how blocking post-translational arginine modifications affects tumor biology in an ex vivo model that preserves tissue architecture and cellular interactions.

Written by the GCMD Library team from the article.

Amr Moursi

Arginine methylation is a post-translational modification that consists of the transfer of one or two methyl (CH3) groups to arginine residues in proteins. Several types of arginine …

Read it at the source ↗