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Incidence of Low-Grade Testicular Injury in Orchidectomy Specimens Post-testicular Torsion
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Read the article on dx.doi.org ↗Article · May 2017 · 1 min read
In brief
In brief
Retrospective 15-year study examining orchidectomy specimens from pediatric testicular torsion cases to determine how often low-grade, potentially reversible testicular injury is removed. Challenges the practice of early orchidectomy when viability is uncertain, given animal studies showing contralateral autoimmune risk but limited human evidence.
Written by the GCMD Library team from the article.
Introduction Following detorsion and orchidopexy for testicular torsion, predominantly animal studies have reported a risk of autoimmune and reperfusion injury to the contralateral testis. As a result, when testicular viability is compromised, orchidectomy is readily performed. This practice increases the likelihood of testes with potentially reversible injury being excised. We aim to determine the incidence of such occurrences and review the available evidence for and against early orchidectomy when testicular viability is doubtful.
Materials and Methods Data for a 15-year period from two pediatric institutions on testicular torsion in children younger than 16 years were reviewed. Using a previously published grading system, the orchidectomy specimens in this cohort with early low-grade injury were analyzed. Low-grade injury suggests the possibility of restitutio ad integrum implying restoration of exocrine and endocrine function of the affected testes.
Results Between both institutions, 222 scrotal explorations were performed for testicular torsion; 20 neonatal and 202 outside the neonatal period (age range [median]: 1–28 days [3 days] and 3 months–16 years [13 years], respectively). Of these scrotal explorations, 17 neonatal and 66 nonneonatal orchidectomies were required (85 vs. 33%, respectively; p
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