Incidence of and Risk Factors for Perioperative Blood Transfusion in Infants Undergoing Index Pediatric Surgery Procedures
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Read the article on jpedsurg.org ↗Article · Feb 2022 · 1 min read
In brief
In brief
Retrospective study of 420 infants undergoing index neonatal operations found a 6% perioperative transfusion rate, with EA/TEF repair and structural heart disease as key risk factors. The findings inform evidence-based pretransfusion testing protocols for high-risk neonatal surgical cases.
Written by the GCMD Library team from the article.
Background
: There is a paucity of data on the frequency of transfusion during pediatric surgery index cases and guidelines for pretransfusion testing, defined as type and screen and crossmatch testing, prior to operation are not standardized. This study aimed to determine the incidence of perioperative blood transfusions during index neonatal operations and identify risk factors associated with perioperative blood transfusion to determine which patients benefit from pretransfusion testing.
Methods
: A retrospective review of infants who underwent index neonatal cases between 2013-2019 was performed. Data were collected for patients who underwent operations for Hirschsprung's disease, esophageal atresia/tracheoesophageal fistula (EA/TEF), biliary atresia, anorectal malformation, omphalocele, gastroschisis, duodenal atresia, congenital diaphragmatic hernia (non-ECMO) or pulmonary lobectomy. Infants under 6 months were included except in the case of lobectomy where infants up to 12 months were included.
Results
: Analysis was performed on 420 patients. Twenty-five (6.0%) patients received perioperative blood transfusion. Patients who received perioperative transfusion most commonly underwent EA/TEF repair. Patients who received perioperative transfusion had higher rates of structural heart disease (52.0% vs 17.7%, p