GER characteristics after fundoplication in children with aerodigestive disorders
jpedsurg.org shows its articles on its own site.
Read the article on jpedsurg.org ↗Article · Nov 2019 · 1 min read
In brief
In brief
Cross-sectional study of 242 pediatric patients with aerodigestive disorders found Nissen fundoplication effectively controls reflux long-term, with median 8.5 reflux episodes per 24 hours and no significant increase over time (1-192 months post-op). Despite functional fundoplications, 58% remained on proton pump inhibitors, suggesting potential overtreatment.
Written by the GCMD Library team from the article.
Purpose
The purpose of this study was to determine GER characteristics after Nissen fundoplication in children with aerodigestive disorders using pH-impedance technology.
Methods
In this cross-sectional study, the institutional database of Cincinnati Children's Hospital Medical Center was reviewed to identify patients ages below 21 years who had a Nissen fundoplication and underwent esophageal pH-impedance (pH-MII) monitoring over a nine-year period. All reflux-related metrics were modeled as a Poisson random variable as a function of time since fundoplication.
Results
A total of 242 patients were included in the study. The range for time since surgery was 1–192 months. Median total reflux events were 8.5 episodes per 24 h, median acidic reflux events were 0, and median proximal reflux event was 2. There was no significant trend towards increasing reflux episodes over time.
Conclusions
Children had a low number of reflux events after a fundoplication, as measured by pH-impedance, and there was no statistically significant increase observed in the number of reflux events over time. Despite most patients having a functional fundoplication with minimal reflux events throughout the entire age range, up to 58% of our cohort was still on a proton pump inhibitor.