Fluorescence imaging in pediatric surgery: State-of-the-art and future perspectives
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Read the article on jpedsurg.org ↗Article · Sep 2020 · 1 min read
In brief
In brief
This systematic review examines the emerging use of fluorescence-guided surgery in pediatric populations, analyzing 21 studies across tumor resection, biliary/urogenital imaging, and perfusion assessment. While clinical evidence remains limited, FGS demonstrates significant potential for improving surgical precision in hepatoblastoma resection and real-time anatomical delineation in pediatric patients.
Written by the GCMD Library team from the article.
Abstract
Background
The employment of fluorescence imaging has gained popularity in many fields of adult surgery where it has demonstrated great potentials to improve both surgical and oncological outcomes while minimizing anesthetic time and lowering health-care costs. However, the clinical application of fluorescence-guided surgery (FGS) in pediatrics is just at the initial phase.
Material and methods
A systematic review of current clinical uses of FGS in pediatric surgery was performed along with a discussion on its advantages, limitations and future developments.
Results
21 studies were included: 9 retrospective and 1 prospective study, 8 case reports, 2 case series and a review article reporting authors' institutional experience. Great emphasis was given to surgical resection of hepatoblastoma and its metastasis (n = 6), real-time imaging of the biliary tree (n = 3) and urogenital system (n = 2). Other current uses concern the assessment of blood perfusion (intestine, n = 3; myocutaneous flap, n = 1; transplanted liver, n = 1) and lymphatic flow imaging (n = 4).
Conclusion
Despite a paucity of clinical studies evaluating its role in pediatric surgery, FGS has shown promising results in helping guide tumor resection and improving the accuracy of anatomical delineation.
Type of study
Review article.
Level of confidence
Level IV.