Feasibility and safety of laparoscopic tumor resection in children with abdominal neuroblastomas
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Read the article on link.springer.com ↗Article · Jan 2023 · 1 min read
In brief
In brief
This retrospective study of 35 pediatric abdominal neuroblastoma cases demonstrates that laparoscopic resection is safe and effective for tumors ≤60mm without image-defined risk factors, achieving complete resection with significantly less blood loss than open surgery. Five-year survival was equivalent between approaches at 93.8%.
Written by the GCMD Library team from the article.
Abstract
Purpose
This study aimed to evaluate the feasibility and safety of laparoscopic resection of abdominal neuroblastoma by comparing operative and long-term oncologic outcomes between open and laparoscopic surgeries.
Methods
This single-center retrospective study included patients who underwent laparoscopic tumor resection, between January 2000 and June 2021, with a maximum tumor diameter of ≤ 60 mm and without image-defined risk factors (IDRFs) at surgery. Data from 35 abdominal neuroblastoma resections were reviewed and compared between the laparotomy and laparoscopic groups.
Results
Nineteen patients underwent laparotomy and 16 had laparoscopic tumor resection. All laparoscopic surgeries achieved complete resection without conversion to open surgery. Median blood loss was significantly lower in the laparoscopic group (0.6 mL/kg) than in the laparotomy group (8.4 mL/kg) (P < 0.0001). There were two locoregional recurrences in the laparoscopic group and two metastatic recurrences in the laparotomy group. Five-year overall survival was 93.8% in both groups.
Conclusion
Laparoscopic resection of abdominal neuroblastomas in children is a feasible and safe procedure for tumors ≤ 60 mm in diameter with no IDRFs at surgery, with long-term outcomes equivalent to laparotomy.