StayCurrentMD · Factors Associated With Short- and Long-term Survival in Oesophageal Atresia With Tracheoesophageal Fistula
Article1 min read·Published Mar 2025

Factors Associated With Short- and Long-term Survival in Oesophageal Atresia With Tracheoesophageal Fistula

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Article · Mar 2025 · 1 min read

In brief

In brief

This multicentre study develops and validates a risk stratification score for predicting survival in neonates with oesophageal atresia and tracheoesophageal fistula (OA-TOF). Using international cohort data, the research addresses limitations of single-centre scoring systems to improve prognostic accuracy for this congenital condition.

  • Existing risk stratification scores for OA-TOF often lack external validity due to single-center derivation.
  • International multicentre cohorts improve the generalizability of survival prediction models in OA-TOF.
  • Validated risk scores enable clinicians to better counsel families on short- and long-term prognosis.
  • Standardized risk assessment tools facilitate outcome benchmarking across pediatric surgical centers.
  • Accurate survival modeling in OA-TOF requires diverse patient populations beyond single institutions.

Written by the GCMD Library team from the article.

Risk stratification scores for oesophageal atresia with tracheoesophageal fistula (OA-TOF) are useful to predict survival. Scores from single-centre series may lack external validity. We aimed to model survival in OA-TOF and validate a new risk score using an international, multicentre cohort of patients.

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