Etiology and prognosis of pediatric short bowel syndrome
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In brief
In brief
This review examines the causes and prognostic factors in pediatric intestinal failure, a life-threatening condition requiring specialized nutritional support. Despite improved survival rates, affected children face serious complications including liver disease, infections, and growth failure, necessitating individualized treatment strategies to achieve independence from parenteral nutrition.
Written by the GCMD Library team from the article.
Publication date: August 2018
Source: Seminars in Pediatric Surgery, Volume 27, Issue 4
Author(s): Annika Mutanen, Paul W. Wales
Abstract
Pediatric intestinal failure is a complex and devastating condition defined as the inability of the intestine to absorb an adequate amount of fluid and nutrients to sustain life. The primary goal of intestinal failure treatment is to achieve enteral autonomy with a customized treatment plan. Although recent improvements in intestinal failure patient care have led to significant improvements in the morbidity and mortality rate, children with intestinal failure are at risk for multiple complications such as intestinal failure associated liver disease, recurrent septic episodes, central line complications, metabolic bone disease, impaired kidney function, and failure to thrive. In this article, we review the current literature on the etiology and factors affecting prognosis of pediatric IF.