Early surgical management for giant omphalocele: Results and prognostic factors
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In brief
In brief
This retrospective study evaluates early surgical management strategies for 29 neonates with prenatally diagnosed giant omphalocele, comparing staged closure versus immediate synthetic patch repair. The analysis examines mortality, morbidity, and prognostic factors, distinguishing between isolated defects and those with associated malformations.
Written by the GCMD Library team from the article.
Objectives
Giant omphalocele often represents a major surgical challenge and is reported with high mortality and morbidity rates. The aim of this study was to assess the outcome of neonates with giant omphalocele managed with early operative surgical treatment, and subsequently to identify possible factors that could alter the prognosis.
Methods
We reviewed the medical records of 29 consecutive newborns with prenatally diagnosed giant omphalocele. In these cases one of two procedures had been performed: either staged closure after silo, or immediate closure with a synthetic patch. The cases were separated into 2 groups: Isolated giant omphalocele (IO group) and giant omphalocele associated with malformation (NIO group).
Results
Infants in the IO group had a lower size of the omphalocele (p