Drain placement in paediatric complicated appendicitis: a systematic review and meta-analysis
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In brief
In brief
This systematic review of 5,108 pediatric patients found that prophylactic drain placement after appendectomy for complicated appendicitis actually increases intra-peritoneal abscess risk and prolongs hospital stay without reducing wound infections. The evidence challenges routine drain use in this population.
Written by the GCMD Library team from the article.
Abstract
Children undergoing appendicectomy for complicated appendicitis are at an increased risk of post-operative morbidity. Placement of an intra-peritoneal drain to prevent post-operative complications is controversial. We aimed to assess the efficacy of prophylactic drain placement to prevent complications in children with complicated appendicitis. A systematic review was performed in accordance with PRISMA guidelines. Cochrane, MEDLINE and Web of Science databases were searched from inception to November 2022 for studies directly comparing drain placement to no drain placement in children ≤ 18 years of age undergoing operative treatment of complicated appendicitis. A total of 5108 children with complicated appendicitis were included from 16 studies; 2231 (44%) received a drain. Placement of a drain associated with a significantly increased risk of intra-peritoneal abscess formation (odds ratio [OR] 1.61, 95% confidence interval [CI] 1.16–2.24, p = 0.004) but there was no significant difference in wound infection rate (OR 1.46, 95% CI 0.74–2.88, p = 0.28). Length of stay was significantly longer in the drain group (mean difference 2.02 days, 95% CI 1.14–2.90, p < 0.001). Although the quality and certainty of the available evidence is low, prophylactic drain placement does not prevent intra-peritoneal abscess following appendicectomy in children with complicated appendicitis.