Does Creating a Dome Reduce Recurrence in Congenital Diaphragmatic Hernia Following Patch Repair?
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Read the article on jpedsurg.org ↗Article · Oct 2021 · 1 min read
In brief
In brief
Retrospective study of 192 neonates with CDH found that creating a dome-shaped prosthetic patch repair (measured by vertical-horizontal diaphragm ratio >20% on chest X-ray) was associated with approximately half the recurrence rate compared to non-dome repairs (14% vs 28%). Authors propose this quantifiable radiographic approach may guide surgical technique to reduce CDH recurrence.
Written by the GCMD Library team from the article.
Purpose
: To develop a quantifiable approach to identify a dome shape of the repaired diaphragm using post-operative chest radiograph and to determine if a dome-shaped prosthetic patch repair is associated with a decreased rate of CDH recurrence.
Methods
: We conducted a retrospective review of all neonates evaluated at our institution from January 2004 to August 2017 with left- and right-sided CDH with at least 6 months of follow-up after CDH repair. Patch use, post-operative imaging and postnatal outcomes were analyzed. Neonates with patch repair were divided into two groups based on the presence of a dome. Using postoperative chest radiographs, the presence of a dome was classified as having a vertical-horizontal diaphragm ratio (VHDR) greater than 20%. Primary outcome was CDH recurrence after repair.
Results
: We identified 192 neonates who met our inclusion criteria. Cohort survival was 96%, recurrence rate was 15%, 78% had a left-sided CDH; 54% received a patch repair, of which 58% had a type C defect. Of the 104 infants with patch repairs, the CDH recurrence rate was 22% (n=23) at a median age of 8.5 months (3.8, 20.1). Although neonates with a dome repair had more ECMO use and longer hospital stay, their recurrence rate was about half of those with a non-dome repair (14% vs 28%, p=0.07).
Conclusions
: A dome-shaped repair may reduce recurrence following prosthetic patch repair of congenital diaphragmatic hernia. A larger, multi-institutional study is needed to statistically validate this clinically significant observation.
Type of Study
: Retrospective Review
Level of Evidence
: III