Differentiating Congenital Ovarian Cysts From Other Abdominal Cystic Lesions In Female Infants: A Study by the Canadian Consortium for Research in Pediatric Surgery (CanCORPS)
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In brief
In brief
Multi-center Canadian study of 185 female infants with prenatally diagnosed abdominal cysts found that 12% were non-ovarian in origin. Earlier gestational age at diagnosis was associated with non-ovarian etiology, helping clinicians distinguish cysts requiring surgical intervention from ovarian cysts managed conservatively.
Written by the GCMD Library team from the article.
Purpose: The origin of congenital abdominal cysts in the female fetus often dictates management. While most arise from the ovary and are often managed non-operatively, some are non-ovarian and are frequently removed. We analyzed a national sample of female infants with congenital abdominal cysts to elucidate prenatal and postnatal factors associated with the diagnosis of a non-ovarian cyst.
Methods: A retrospective cohort study of female infants who were prenatally diagnosed with abdominal cysts between 2013 and 2017 at 10 Canadian pediatric surgical centres was performed. Clinical characteristics, pre- and postnatal sonographic findings, and cyst trajectories were compared between patients with proven ovarian etiology and those with cysts arising from other organs.
Results: Of 185 infants with prenatally diagnosed abdominal cysts, 22 (12%) were non-ovarian, five of which had clear non-ovarian organ of origin on prenatal ultrasound. Comparison of the other 17 cysts with 163 congenital ovarian cysts showed the following factors to be associated with a non-ovarian origin: earlier gestational age at diagnosis (23.5 vs 33.5 weeks, p