Development of a prediction model for postoperative complications after primary hypospadias correction
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In brief
In brief
Retrospective study of 356 patients developed a prediction model for complications after one-stage hypospadias correction, achieving good accuracy (C-statistic 0.70) using hypospadias phenotype, surgical technique, chordectomy, and surgeon experience. The model can improve preoperative counseling by providing individualized risk estimates for anterior and middle hypospadias repairs.
Written by the GCMD Library team from the article.
Purpose
To develop a prediction model for postoperative complications after primary one-stage hypospadias correction to improve preoperative parental counseling.
Materials and methods
In this retrospective cohort study, data were collected from 356 patients with anterior or middle hypospadias who had a one-stage hypospadias correction from 2003 onwards. Potential treatment- and patient-related factors were selected and used to develop a prediction model for postoperative complications within one year (wound-related complications, urinary tract infections, fistulas, stenosis, and prepuce-related complications). Multivariable logistic regression analysis with stepwise backward selection and a p-value of 0.20 was used to select the final model, which was internally validated using the bootstrap procedure.
Results
Complications within one year postoperatively occurred in 66 patients (19%), of which 13% and 37% were seen in anterior and middle type of hypospadias, respectively. Hypospadias phenotype, surgical technique, chordectomy, and surgeon's experience were included in the final prediction model, whereas none of the patient-related factors were. The final model had a good discriminative ability (bias corrected C statistic 0.70) and calibration.
Conclusion
Using easily obtainable information, this model showed good accuracy in predicting complications within one year after hypospadias surgery. It is a first step towards individualized risk prediction of postoperative complications for anterior and middle hypospadias and can assist in preoperative parental counseling.
Type of study
Prognostic study.
Level of evidence
Level II.