Delivery planning for Congenital Lung Malformations: A CVR based perinatal care algorithm
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Read the article on jpedsurg.org ↗Article · Jan 2022 · 1 min read
In brief
In brief
This retrospective study validates a CVR threshold of ≥1.1 for predicting urgent perinatal surgical intervention in congenital lung malformations, proposing a delivery planning algorithm based on late-gestation ultrasound measurements. The research analyzed 65 CLM cases to establish evidence-based criteria for delivery location and timing decisions.
Written by the GCMD Library team from the article.
Purpose
Congenital lung malformation (CLM) volume ratio (CVR) of ≥1.1 has been shown to be highly predictive of the need for urgent, perinatal surgical intervention. The purpose of this study was to utilize this information to propose a delivery planning and clinical management algorithm based on this threshold.
Methods
A retrospective cohort study was performed for all fetuses evaluated at our fetal center between 5/2015 and 11/2020. Demographics, ultrasound findings, late gestation CVR (≥27 weeks gestational age), prenatal and postnatal treatment, and outcomes were analyzed with nonparametric univariate analysis based on late gestation CVR of 1.1. Receiver operating characteristic curve analysis was performed to evaluate association between late gestation CVR, hydrops, need for fetal intervention, and need for urgent perinatal surgery.
Results
Of the 90 CLMs referred to our fetal center, 65 had late gestation CVR with a majority