Cystic fibrosis and portal hypertension: Distal splenorenal shunt can prevent the need for future liver transplant
jpedsurg.org shows its articles on its own site.
Read the article on jpedsurg.org ↗Article · Feb 2019 · 1 min read
In brief
In brief
This study evaluates distal splenorenal shunt (DSRS) as an alternative to liver transplantation for managing portal hypertension in children with cystic fibrosis and compensated cirrhosis. Between 2008-2017, five CF patients underwent DSRS while nine with decompensated disease received transplants, demonstrating DSRS as a viable bridge therapy.
Written by the GCMD Library team from the article.
Background
The management of portal hypertension (PHT) in children with well compensated cirrhosis and cystic fibrosis (CF) is controversial. We present our experience with distal splenorenal shunting (DSRS) for the treatment of PHT as an alternative to liver transplantation (LT).
Methods
Between 2008 and 2017, 5 CF children underwent a DSRS at a pediatric hepatobiliary and transplantation referral center. LT (n = 9) was reserved for patients with decompensated cirrhosis. Statistical analysis was done using the paired t-test (p